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NANOSPRESSO Revolutionizing orphan disease care with bedside nucleic acid nanomedicine production. A European 6-year project funded by Dutch Research Council.

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THE CHALLENGE

Empowering Change in Orphan Disease Care: Confronting Therapy Complexities

Millions of patients struggle with rare diseases worldwide, yet treatment breakthroughs are also rare. Despite their immense potential, novel therapies, such as nucleic acid-based therapeutics, face hurdles including manufacturing, characterization and regulatory challenges. Our mission: to finally make innovative personalised treatments a reachable goal.
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OUR SOLUTION

Localised Production of Nanomedicine: Introducing the Next Generation of Compounding

NANOSPRESSO wants to revolutionise the paradigm of nanomedicine, through a decentralised manufacturing approach. Our cutting-edge technology will allow for small-scale production of high-quality nucleic acid medicines, directly in hospital pharmacies or research centres.
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Perspectives from Industry Experts and Stakeholders

For rare diseases, commercial therapies are not always in the best interest of patients and society. NANOSPRESSO merges platform technologies to allow local hospitals to make high quality nucleic acid nanomedicines at the bedside.

Prof. Raymond Schiffelers (UMC Utrecht)
NANOSPRESSO Project Coordinator

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PERSONALISED MEDICINE

A Platform Approach for Customised Therapies for Orphan Diseases

NANOSPRESSO-NL is pioneering a platform, not just a product. By adapting the nucleic acid sequences, without changing the formulation process, we can tailor treatments for specific diseases or even individual patient profiles, from rare paediatric metabolic disorders to cancer, setting a new standard in personalised healthcare.
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EMPOWERMENT

Cultivating a Collaborative Standard of Care between patients & clinicians

Central to our solution are the patients and their physicians, who identify urgent clinician needs. NANOSPRESSO will provide them with a flexible technology, allowing the local pharmacists to produce custom therapeutics right at the hospital, tailored to the needs of individual patients. From a one-size-fits-all model to a local collaborative strategy for rare and orphan diseases.
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OUR ENGINE

An inclusive and diverse R&D consortium to solve a global unmet clinical need

NANOSPRESSO is driven by a unique consortium of European partners, with its core group in the Netherlands. This 6-year multi-disciplinary project unites an ecosystem of healthtech developers, clinicians, regulators, public researchers, innovative SMEs and many more in a concerted effort to deliver a groundbreaking nanomedicine solution to real societal needs.
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LOCAL PREPARATION OF HIGH-QUALITY, PERSONALISED NUCLEIC ACID NANOMEDICINES

NANOSPRESSO is funded by the Dutch Research Agenda (NWA) ORC 2020/21 program. For more information about our partners, funding, and legal notices, please visit our contact page and follow us on social media.